Sentinel lymph node biopsy results in less postoperative morbidity compared with axillary lymph node dissection for breast cancer

Background: This study was designed to compare the postoperative morbidity and socioeconomic impact of sentinel lymph node biopsy (SLNB) with axillary lymph node dissection (ALND) in patients with early stage breast cancer. Methods: A prospective, nonrandomized, controlled study was designed to incl...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of surgery 2002, Vol.183 (1), p.23-27
Main Authors: Burak, William E, Hollenbeck, Scott T, Zervos, Emmanuel E, Hock, Karen L, Kemp, Lisa C, Young, Donn C
Format: Article
Language:English
Subjects:
Activities of daily living
Aged
Arm circumference
Axilla - pathology
Biological and medical sciences
Biopsy
Breast
Breast cancer
Breast Neoplasms - pathology
Breast Neoplasms - surgery
Cancer therapies
Chemotherapy
Circumferences
Dissection
Edema
Female
Hospitals
Humans
Localization
Lymph Node Excision - adverse effects
Lymph Node Excision - methods
Lymph nodes
Lymphatic Metastasis - diagnosis
Lymphatic system
Lymphedema
Mammography
Medical sciences
Middle Aged
Morbidity
Neoplasm Staging
Patients
Postoperative Complications - epidemiology
Postoperative Complications - prevention & control
Postoperative period
Prospective Studies
Questionnaires
Radiation
Sentinel
Sentinel Lymph Node Biopsy - adverse effects
Sentinel Lymph Node Biopsy - methods
Social Class
Socioeconomics
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the genital tract and mammary gland
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: This study was designed to compare the postoperative morbidity and socioeconomic impact of sentinel lymph node biopsy (SLNB) with axillary lymph node dissection (ALND) in patients with early stage breast cancer. Methods: A prospective, nonrandomized, controlled study was designed to include patients who underwent breast conservation surgery and SLNB ± ALND. Group A consisted of patients who had a negative SLNB and did not go on to completion ALND. Group B consisted of patients who underwent a SLNB followed by a completion ALND because either (1) their sentinel node contained cancer or (2) they were within the validation phase of our institution’s sentinel lymph node protocol. Patients were evaluated with a questionnaire and underwent a standardized physical examination to determine arm circumference. Results: Data were obtained from 96 patients with a mean follow-up period of 15 months (range 8 to 29). Significant differences were seen in subjective measurements of arm complaints and arm numbness ( P
ISSN:0002-9610
1879-1883
DOI:10.1016/S0002-9610(01)00848-0