Influence of heart rate on vessel visibility in noninvasive coronary angiography using new multislice computed tomography: Experience in 94 patients

Objectives: Initial reports indicate that coronary artery lesions might be visualized with high sensitivity and specificity by the use of recently introduced multislice computed tomography (MSCT). Current CT technology offers a temporal resolution of 250 ms. In case of heart rates (HRs) >65 beats...

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Bibliographic Details
Published in:Clinical imaging 2002-03, Vol.26 (2), p.106-111
Main Authors: Schroeder, Stephen, Kopp, Andreas F, Kuettner, Axel, Burgstahler, Christof, Herdeg, Christian, Heuschmid, Martin, Baumbach, Andreas, Claussen, Claus D, Karsch, Karl R, Seipel, Ludger
Format: Article
Language:English
Subjects:
Adult
Analysis of Variance
Biological and medical sciences
Cardiovascular imaging
Cardiovascular system
Coronary Angiography
Coronary artery disease (CAD)
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - physiopathology
Coronary Vessels - physiopathology
Female
Heart rate
Heart Rate - physiology
Humans
Image Processing, Computer-Assisted
Image reconstruction
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Multislice computed tomography (MSCT)
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Sensitivity and Specificity
Tomography, X-Ray Computed - methods
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Summary:Objectives: Initial reports indicate that coronary artery lesions might be visualized with high sensitivity and specificity by the use of recently introduced multislice computed tomography (MSCT). Current CT technology offers a temporal resolution of 250 ms. In case of heart rates (HRs) >65 beats/min (bpm), however, the reconstruction software switches from a single-phase algorithm (using data from one heart cycle only) to a biphase algorithm using image data of two consecutive heart cycles, improving temporal resolution to down to 125 ms. Thus, it was the aim of the present study to evaluate the influence of the patients' (pts) HR on image quality expressed by vessel segment visibility. Methods and results: MSCT scans (Somatom VZ) were performed in 94 pts. Ten coronary segments were analyzed in each patient with regard to image quality (RCA: segments [sgts] 1–4, LMS: sgt 5, LAD: sgts 5–8, LCX: sgts 11, 12). A total of 697 of 940 (74.1%) sgts were accurately visualizable (RCA: 244/376 [64.9%], LMS: 94/94 [100%], LAD: 232/283 (82.3%), LCX: 146/188 [77.7%]). β-Blocker therapy had a significant influence on mean HR (65 pts on β-blocker, HR 65.1±10.7 bpm vs. 29 pts, HR 71.6±12.2 bpm, P=.01). A significant inverse correlation between HR and segmental visibility was found ( r=−.48, P
ISSN:0899-7071
1873-4499
DOI:10.1016/S0899-7071(01)00371-0