What keeps serum calcium levels stable?

Many body functions require that serum calcium levels remain stable over time. This stability is provided by cooperation among three organs: two effectors, the bone and the kidney, which control calcium movements into and out of the extracellular compartment, and the parathyroid glands, which produc...

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Bibliographic Details
Published in:Joint Bone Spine 2003-12, Vol.70 (6), p.407-413
Main Authors: Houillier, Pascal, Nicolet-Barousse, Laurence, Maruani, Gérard, Paillard, Michel
Format: Article
Language:English
Subjects:
Bone
Bone and Bones - metabolism
Calcium
Calcium - analysis
Calcium - metabolism
Calcium Signaling - physiology
Calcium-sensing receptor
Humans
Kidney
Kidney - metabolism
Parathyroid Glands - metabolism
Parathyroid hormone
Parathyroid Hormone - metabolism
Receptors, Calcium-Sensing - metabolism
Water-Electrolyte Balance - physiology
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Summary:Many body functions require that serum calcium levels remain stable over time. This stability is provided by cooperation among three organs: two effectors, the bone and the kidney, which control calcium movements into and out of the extracellular compartment, and the parathyroid glands, which produce and release parathyroid hormone (PTH). PTH acts on the bone and renal tubule. Provided the amount released is appropriate, this keeps extracellular calcium levels stable.
ISSN:1297-319X
1778-7254
DOI:10.1016/S1297-319X(03)00052-6