Diffusion‐weighted MR findings of central pontine and extrapontine myelinolysis

Diffusion‐weighted MR (DWI) can detect changes in water diffusion associated with cellular dysfunction, which enables the differentiation of cytotoxic edema from vasogenic edema. In this study on DWI findings in central pontine (CPM) and extrapontine myelinolysis (EPM), DWI showed high signal intens...

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Bibliographic Details
Published in:Acta neurologica Scandinavica 2001-12, Vol.104 (6), p.385-388
Main Authors: Chu, K., Kang, D.‐W., Ko, S.‐B., Kim, M.
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
central pontine myelinolysis (CPM)
cytotoxic edema
diffusion‐weighted MR
extrapontine myelinolysis (EPM)
Female
Humans
Magnetic Resonance Imaging
Medical sciences
Mesencephalon - pathology
Myelinolysis, Central Pontine - pathology
Nervous system (semeiology, syndromes)
Nervous system as a whole
Neurology
Pons - pathology
Tropical medicine
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Description
Summary:Diffusion‐weighted MR (DWI) can detect changes in water diffusion associated with cellular dysfunction, which enables the differentiation of cytotoxic edema from vasogenic edema. In this study on DWI findings in central pontine (CPM) and extrapontine myelinolysis (EPM), DWI showed high signal intensities in the bilateral pons, midbrain, and genu of the corpus callosum. The corresponding apparent diffusion coefficient values were rather low. This suggests that cytotoxic edema does in fact exist in CPM and EPM and that DWI can be useful in the rapid diagnosis and prediction of the various types of edema occurring in active demyelinating diseases.
ISSN:0001-6314
1600-0404
DOI:10.1034/j.1600-0404.2001.00096.x