Effect of gaseous media on the balance between cardiac outputs of the right and left ventricles

Acute experiments on cats showed that mild hypoxia did not disturb the balance between right and left ventricular outputs. Breaching 3% O(2) shifted this balance by reducing right ventricular output in cats with low resistance to hypoxia. Spontaneous breathing hypercapnic gas mixtures shifted this b...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2001-11, Vol.132 (5), p.1051-1054
Main Authors: Sanotskaya, N V, Matsievskii, D D
Format: Article
Language:English
Subjects:
Animals
Aorta - physiology
Cats
Epinephrine - pharmacology
Female
Heart Ventricles - drug effects
Hemodynamics
Histamine - pharmacology
Hypoxia
Male
Myocardium - metabolism
Norepinephrine - pharmacology
Oxygen - metabolism
Time Factors
Vasoconstrictor Agents - pharmacology
Ventricular Function
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Summary:Acute experiments on cats showed that mild hypoxia did not disturb the balance between right and left ventricular outputs. Breaching 3% O(2) shifted this balance by reducing right ventricular output in cats with low resistance to hypoxia. Spontaneous breathing hypercapnic gas mixtures shifted this balance towards the left ventricular output. During artificial ventilation under open chest conditions, hypercapnia induced opposite changes and shifted the balance towards the right ventricular output.
ISSN:0007-4888
1573-8221