Familial chronic lymphocytic leukemia

Familial aggregation of chronic lymphocytic leukemia (CLL) has been observed more frequently than familial aggregation of any other type of oncohematologic disorder. The presence of cells with a CLL-like immunophenotype (CLL-like cells) was recently documented in 13.5% healthy first-degree relatives...

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Bibliographic Details
Published in:Haematologica (Roma) 2003-10, Vol.88 (10), p.1190-1191
Main Authors: Cerny, J, Slavickova, A, Krepelova, A, Trneny, M, Karban, J, Klener, P
Format: Article
Language:English
Subjects:
Female
Humans
Leukemia, Lymphocytic, Chronic, B-Cell - genetics
Male
Middle Aged
Online Access:Get full text
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Summary:Familial aggregation of chronic lymphocytic leukemia (CLL) has been observed more frequently than familial aggregation of any other type of oncohematologic disorder. The presence of cells with a CLL-like immunophenotype (CLL-like cells) was recently documented in 13.5% healthy first-degree relatives of CLL patients. We present a family with CLL in which 2 brothers, a sister and their mother were affected.
ISSN:0390-6078
1592-8721