Clinical and Cost Outcomes of Medical Nutrition Therapy for Hypercholesterolemia: A Controlled Trial

Objective To compare the results and cost-effectiveness of a cholesterol lowering protocol implemented by registered dietitians with cholesterol lowering advice by physicians. Design Six month randomized controlled trial, cost-effectiveness analysis. Subjects included 90 ambulatory care patients (60...

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Bibliographic Details
Published in:Journal of the American Dietetic Association 2001-09, Vol.101 (9), p.1012-1023
Main Authors: DELAHANTY, LINDA M, SONNENBERG, LILLIAN M, HAYDEN, DOUG, NATHAN, DAVID M
Format: Article
Language:English
Subjects:
Adult
Aged
Analysis of Variance
Anticholesteremic agents
Anticholesteremic Agents - economics
Anticholesteremic Agents - therapeutic use
Biological and medical sciences
Body Weight - drug effects
Cholesterol
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Cost-Benefit Analysis
Diet
Diet, Fat-Restricted - economics
Dietary Fats - administration & dosage
Dietary Services - economics
Dietetics
Disorders of blood lipids. Hyperlipoproteinemia
Exercise
Feeding Behavior
Female
Humans
Hypercholesterolemia - diet therapy
Hypercholesterolemia - drug therapy
Hypercholesterolemia - economics
Life Style
Lipids - blood
Male
Medical sciences
Metabolic diseases
Middle Aged
Nutrition
Nutrition education
Outcome Assessment (Health Care)
Patient Satisfaction
Statistical analysis
Treatment Outcome
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Summary:Objective To compare the results and cost-effectiveness of a cholesterol lowering protocol implemented by registered dietitians with cholesterol lowering advice by physicians. Design Six month randomized controlled trial, cost-effectiveness analysis. Subjects included 90 ambulatory care patients (60 men, 30 women), age range 21 to 65 years, with hypercholesterolemia and not taking hypolipidemic drugs. Patients were randomly assigned to receive medical nutrition therapy (MNT) from dietitians using a NCEP based lowering protocol or usual care (UC) from physicians. Outcome measures were plasma lipid profiles, dietary intake, weight, activity, patient satisfaction, and costs of MNT. Changes from baseline for each variable of interest were compared between treatment groups using analysis of covariance controlling for baseline value of the variable and gender. Results MNT achieved a 6% decrease in total and LDL cholesterol levels at 3 and 6 months compared with a 1% increase and a 2% decrease in both values at 3 and 6 months with UC ( P
ISSN:0002-8223
2212-2672
1878-3570
2212-2680
DOI:10.1016/S0002-8223(01)00250-4