Changing epidemiological features of Subacute sclerosing panencephalitis

Subacute sclerosing panencephalitis (SSPE) is a chronic central nervous (CNS) system infection caused by measles virus. Because changing immunization practices affect the epidemiology of measles and consequently SSPE, we examined the epidemiological data of our SSPE registry. Age of onset, age at on...

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Bibliographic Details
Published in:Infection 2001-08, Vol.29 (4), p.192-195
Main Authors: ANLAR, B, KÖSE, G, GÜRER, Y, ALTUNBASAK, S, HASPOLAT, S, OKAN, M
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Distribution
Age of Onset
Biological and medical sciences
Child
Child, Preschool
Female
Human viral diseases
Humans
Incidence
Infant
Infectious diseases
Male
Measles - complications
Measles - prevention & control
Measles Vaccine - therapeutic use
Medical sciences
Risk Factors
Subacute Sclerosing Panencephalitis - epidemiology
Subacute Sclerosing Panencephalitis - prevention & control
Subacute Sclerosing Panencephalitis - virology
Tropical medicine
Turkey - epidemiology
Viral diseases
Viral diseases of the nervous system
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Summary:Subacute sclerosing panencephalitis (SSPE) is a chronic central nervous (CNS) system infection caused by measles virus. Because changing immunization practices affect the epidemiology of measles and consequently SSPE, we examined the epidemiological data of our SSPE registry. Age of onset, age at onset of measles, duration of Latent period and immunization status were examined in cases recorded at the SSPE Registry Center in Turkey between 1975 and 1999. Age of onset diminished from 13 years before 1994 to 7.6 years after 1995; age at onset of measles declined from 29 months to 20 months and the Latent interval from 9.9 years to 5.9 years. Age at onset of measles and immunization status did not directly affect the duration of the Latent period. Although its incidence has decreased in Turkey, SSPE has been seen at younger ages in recent years. This change cannot be attributed solely to younger age at onset of measles. Factors affecting the duration of the Latent period should be investigated further.
ISSN:0300-8126
1439-0973
DOI:10.1007/s15010-001-1115-9