Neonatal nonbacterial thrombotic endocarditis

Nonbacterial thrombotic endocarditis is not widely known in neonates. We report three new cases which illustrate some specific aspects of this pathology. Respiratory distress with severe pulmonary hypertension, systemic hypotension and disseminated intravascular coagulopathy in a full-term newborn w...

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Bibliographic Details
Published in:Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2001-08, Vol.8 (8), p.824-827
Main Authors: Pedespan, L, Amram, D, Sarlangue, J, Mansir, T, Fayon, M, Demarquez, J L
Format: Article
Language:fre
Subjects:
Diagnosis, Differential
Disseminated Intravascular Coagulation - etiology
Echocardiography
Endocarditis - diagnosis
Endocarditis - diagnostic imaging
Endocarditis - pathology
Humans
Hypertension, Pulmonary - etiology
Hypotension - etiology
Infant, Newborn
Infant, Newborn, Diseases - diagnosis
Infant, Newborn, Diseases - diagnostic imaging
Infant, Newborn, Diseases - pathology
Male
Respiratory Distress Syndrome, Newborn - etiology
Risk Factors
Thrombosis - complications
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Summary:Nonbacterial thrombotic endocarditis is not widely known in neonates. We report three new cases which illustrate some specific aspects of this pathology. Respiratory distress with severe pulmonary hypertension, systemic hypotension and disseminated intravascular coagulopathy in a full-term newborn were characteristic findings. An early echocardiography should lead to accurate diagnosis. Hypoxemia and genetic factors could be determining factors in its pathogenesis.
ISSN:0929-693X
1769-664X
DOI:10.1016/S0929-693X(01)00541-3