Left atrial appendage function in patients with different pacing modes

Many studies suggest that patients who receive a ventricular pacemaker have a higher incidence of systemic thromboembolism compared to patients receiving a physiological pacemaker. However, the exact mechanism regarding the etiology of thromboembolism remains unclear. We evaluated the left atrial ap...

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Bibliographic Details
Published in:International journal of cardiology 2000-04, Vol.73 (2), p.135-141
Main Authors: Ertaş, Fatih, Güleç, Sadi, Dinçer, Irem, Erol, Çetin, Tutar, Eralp, Güldal, Muharrem, Karaoğuz, Remzi, Oral, Derviş
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Atrial Function, Left - physiology
Biological and medical sciences
Blood Flow Velocity - physiology
Cardiac Pacing, Artificial - adverse effects
Cardiac Pacing, Artificial - methods
Diseases of the cardiovascular system
Echocardiography
Female
Follow-Up Studies
Heart Block - diagnostic imaging
Heart Block - therapy
Heart Rate
Humans
Left atrial appendage
Male
Medical sciences
Middle Aged
Pacing mode
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Sick Sinus Syndrome - diagnostic imaging
Sick Sinus Syndrome - therapy
Stroke Volume - physiology
Thromboembolism - diagnostic imaging
Thromboembolism - etiology
Transesophageal echocardiography
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Summary:Many studies suggest that patients who receive a ventricular pacemaker have a higher incidence of systemic thromboembolism compared to patients receiving a physiological pacemaker. However, the exact mechanism regarding the etiology of thromboembolism remains unclear. We evaluated the left atrial appendage (LAA) functions, using multiplane transesophageal echocardiography (TEE), in patients with different pacing modes. In order to evaluate the ejection fraction (EF), peak emptying (V E) and filling (V F) flow velocities of the LAA by TEE, we studied 31 patients (mean age 63±18.5 years) who had been paced for 5.0±2.9 years. Patients with atrial fibrillation, left ventricular dysfunction and mitral valve disease were excluded. The pacing indications were complete atrioventricular block (AVB) in 19 patients (9 VVI, 10 VDD or DDD) and sick sinus syndrome (SSS) in 12 patients (5 VVI, 7 DDD). Mean EF, V E and V F of the LAA were significantly lower in all patients with ventricular pacing (25.5±15.6%, 30.4±15.6 cm/s and 29.1±19.2 cm/s, respectively) compared to those with physiologic pacing (48.5±16.9%, 59.6±16.3 cm/s, 57.9±18.5 cm/s, respectively) ( P
ISSN:0167-5273
1874-1754
DOI:10.1016/S0167-5273(99)00221-1