Staphylococcus epidermidis with Intermediate Resistance to Vancomycin: Elusive Phenotype or Laboratory Artifact?

The recent and troubling isolation of Staphylococcus aureus and coagulase-negative staphylococci that have increased resistance to glycopeptide antibiotics has prompted the use of aggressive surveillance measures in the clinical microbiology laboratory to aid in the recognition of these strains. Des...

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Bibliographic Details
Published in:Clinical infectious diseases 2001-07, Vol.33 (1), p.135-137
Main Authors: Dunne, William Michael, Qureshi, Hina, Pervez, Hassan, Nafziger, Daniel A.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Brief Report
Catheters, Indwelling - adverse effects
Drug Resistance, Microbial
Female
Glycopeptides
Humans
Infections
Laboratories
Medical sciences
Microbiology
Middle Aged
Peritoneal Dialysis, Continuous Ambulatory - adverse effects
Peritonitis
Peritonitis - microbiology
Pharmacology. Drug treatments
Phenotype
Phenotypes
Preventive medicine
Staphylococcal Infections - microbiology
Staphylococcus
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus epidermidis - classification
Staphylococcus epidermidis - drug effects
Subcultures
Vancomycin - pharmacology
Vancomycin Resistance
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Summary:The recent and troubling isolation of Staphylococcus aureus and coagulase-negative staphylococci that have increased resistance to glycopeptide antibiotics has prompted the use of aggressive surveillance measures in the clinical microbiology laboratory to aid in the recognition of these strains. Despite increasing awareness, the confirmation of glycopeptide resistance among staphylococci can be problematic; we present a case of catheter-associated peritonitis caused by Staphylococcus epidermidis to illustrate the dilemma.
ISSN:1058-4838
1537-6591
DOI:10.1086/320890