Stress–strain behavior of the passive basilar artery in normotension and hypertension

Abstract Vascular cells are very responsive to even subtle changes in their local mechanical environment, thus there is a pressing need to quantify normal states of stress and strain as well as any perturbations from these normal states. Toward this end, we must quantify constitutive behaviors for b...

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Bibliographic Details
Published in:Journal of biomechanics 2007-01, Vol.40 (11), p.2559-2563
Main Authors: Hu, J.-J, Baek, S, Humphrey, J.D
Format: Article
Language:English
Subjects:
Basilar Artery - physiology
Behavior
Biomechanics
Blood Pressure
Cerebral artery
Collagen
Humans
Hypertension
Models, Cardiovascular
Models, Theoretical
Physical Medicine and Rehabilitation
Stiffness
Strain
Stress
Stress, Mechanical
Studies
Veins & arteries
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Summary:Abstract Vascular cells are very responsive to even subtle changes in their local mechanical environment, thus there is a pressing need to quantify normal states of stress and strain as well as any perturbations from these normal states. Toward this end, we must quantify constitutive behaviors for both normal and adapted (maladapted) arteries. In this note, we report the first quantification of changes in the biaxial mechanical behavior of the passive basilar artery due to hypertension.
ISSN:0021-9290
1873-2380
DOI:10.1016/j.jbiomech.2006.11.007