Tissue Doppler Echocardiography Reveals Insufficient Contractile Reserve Recruitment during Effort in Subjects with Mitral Valve Prolapse and Those with Thick Mitral Valve

Objective: To assess by tissue Doppler echocardiography (TDE), the tissue velocities, both at rest and after exercise stress testing, in subjects with mitral valve prolapse (MVP) and those with thick mitral valve (TMV). Methods: Twenty individuals with typical MVP, 30 with TMV, and 30 healthy contro...

Full description

Saved in:
Bibliographic Details
Published in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2006-02, Vol.23 (2), p.114-119
Main Authors: Zampoulakis, John D., Karavidas, Apostolos I., Matsakas, Evangellos, Lazaros, George A., Karaminas, Naoum T., Fotiadis, Ioannis N., Panou, Fotis K., Zacharoulis, Apostolos
Format: Article
Language:English
Subjects:
Adult
Aged
Analysis of Variance
Case-Control Studies
Echocardiography, Doppler
Exercise Test
Female
Humans
Male
Middle Aged
mitral valve
Mitral Valve - diagnostic imaging
Mitral Valve - physiopathology
mitral valve prolapse
Mitral Valve Prolapse - diagnostic imaging
Mitral Valve Prolapse - physiopathology
Myocardial Contraction
myocardial velocity
tissue Doppler echocardiography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective: To assess by tissue Doppler echocardiography (TDE), the tissue velocities, both at rest and after exercise stress testing, in subjects with mitral valve prolapse (MVP) and those with thick mitral valve (TMV). Methods: Twenty individuals with typical MVP, 30 with TMV, and 30 healthy controls were enrolled. TDE was performed at the basal‐inferior wall and the parameters evaluated were the S, Em, and Am velocities, as well as the Em/Am ratio. Results: The mean S‐wave at rest was higher in subjects with MVP compared to that of the TMV (P < 0.01) and the control groups (P = 0.00005), whereas after exercise it was higher in the control group compared to either MVP (P = 0.013) or TMV group (P = 0.00002). The mean Em wave at rest was higher in the control individuals both at rest (P = 0.007 compared with MVP group and P = 0.013 compared with TMV group), and after exercise (P = 0.0002 and 0.0009, respectively). The Am wave in the MVP group was higher compared with TMV and control subjects at rest (P = 0.022 and 0.00001, respectively) but it was not after exercise (P = ns for both comparisons). The Em/Am ratio of the control group at rest was higher than that of the MVP (P = 0.0000) and TMV (P = 0.00028) groups. However, after exercise, it was higher only when compared with the MVP group (P = 0.016). Conclusions: Subjects with MVP and those with TMV exhibit a less effective contractile response to exercise compared to healthy individuals. Some degree of diastolic dysfunction, particularly after exercise, was also detected in the individuals with MVP. (ECHOCARDIOGRAPHY, Volume 23, February 2006)
ISSN:0742-2822
1540-8175
DOI:10.1111/j.1540-8175.2006.00184.x