Predictors of Target Lesion Revascularization and Documented Stent Thrombosis Beyond 30 Days After Sirolimus-Eluting Stent Implantation: Retrospective Analysis in Consecutive 1,070 Angiographic Follow-up Lesions

Background Outcomes after sirolimus-eluting stent (SES: Cypher®) implantation remained to be elucidated in Japan. Methods and Results Among 1,070 consecutive angiographic follow-up lesions, 99 lesions underwent target lesion revascularization (TLR) with in-stent restenosis (ISR). Retrospective estim...

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Bibliographic Details
Published in:Circulation Journal 2007, Vol.71(8), pp.1328-1331
Main Authors: Mutoh, Makoto, Ishikawa, Tetsuya, Hasuda, Toshio, Okada, Hisayuki, Endo, Akira, Miyanaga, Satoru, Higashitani, Michiaki, Nakano, Yosuke, Kubota, Takeyuki, Nakata, Koutarou, Nagoshi, Tomohisa, Hayashi, Mayuri, Sakamoto, Hiroshi, Oota, Masato, Imai, Kamon, Mochizuki, Seibu
Format: Article
Language:English
Subjects:
Coronary Angiography
Female
Graft Occlusion, Vascular
Humans
Male
Myocardial Revascularization
Percutaneous coronary intervention
Predictive Value of Tests
Prognosis
Restenosis
Retrospective Studies
Revascularization
Sirolimus - administration & dosage
Sirolimus-eluting stent
Stent thrombosis
Stents - adverse effects
Thrombosis - etiology
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Summary:Background Outcomes after sirolimus-eluting stent (SES: Cypher®) implantation remained to be elucidated in Japan. Methods and Results Among 1,070 consecutive angiographic follow-up lesions, 99 lesions underwent target lesion revascularization (TLR) with in-stent restenosis (ISR). Retrospective estimation by multivariate analysis including 50 variables showed that the ostiums of right coronary and left circumflex arteries, hemodialysis, calcification, non-direct stenting, ISR of SES, and non-eccentric lesion were the predictors of TLR. There was no documented late stent thrombosis (LST) among 2,166 lesions and very LST (VLST) among 1,423 lesions. Conclusion Further revises are needed to implant SES to these predictive lesions. LST and VLST were very rare. (Circ J 2007; 71: 1328 -1331)
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.71.1328