Evaluation of pleomorphic xanthoastrocytoma by use of positron emission tomography with

We present a case of pleomorphic xanthoastrocytoma (PXA) in a patient with temporal lobe seizures. Imaging sequences included MR, and results of positron emission tomography (PET) with [18F]-fluorodeoxyglucose (FDG) and [11C]-methionine (Met) tracers revealed a hypermetabolic region equivalent or ne...

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 2001-02, Vol.22 (2), p.311-313
Main Authors: Tsuyuguchi, N, Matsuoka, Y, Sunada, I, Matsusaka, Y, Haque, M
Format: Article
Language:English
Subjects:
Adult
Astrocytoma - diagnosis
Astrocytoma - diagnostic imaging
Astrocytoma - pathology
Brain Neoplasms - diagnosis
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - pathology
Carbon Radioisotopes
Female
Fluorodeoxyglucose F18
Humans
Magnetic Resonance Imaging
Methionine
Radiography
Radiopharmaceuticals
Tomography, Emission-Computed
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Summary:We present a case of pleomorphic xanthoastrocytoma (PXA) in a patient with temporal lobe seizures. Imaging sequences included MR, and results of positron emission tomography (PET) with [18F]-fluorodeoxyglucose (FDG) and [11C]-methionine (Met) tracers revealed a hypermetabolic region equivalent or nearly equivalent to normal cerebral cortex, suggesting that the tumor might have malignant potential. Histopathologic findings indicated low-grade glioma. The mechanism for glucose hypermetabolic activity of PXA is not clear; however, the positive findings obtained from FDG-PET may not always indicate the degree of malignancy associated with PXA.
ISSN:0195-6108
1936-959X