Conjugal multiple sclerosis in Isfahan, Iran: a population-based study

Conjugal multiple sclerosis (MS) is a rare form of MS in which both spouses are affected, and at least one is affected after marriage. Among 1606 definite MS patients, 1076 were in marital relationship, among whom we identified six conjugal pairs, giving the conjugal rate of 0.5%. This rate is 12.5...

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Bibliographic Details
Published in:Multiple sclerosis 2007-06, Vol.13 (5), p.673-675
Main Authors: Maghzi, A.H., Etemadifar, M., Shaygannejad, V., Saadatnia, M., Salehi, M., Hassanzadeh, A.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Child
Cross-Sectional Studies
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Environment
Female
Humans
Immunomodulators
Iran - epidemiology
Male
Medical sciences
Middle Aged
Multiple Sclerosis - epidemiology
Multiple Sclerosis - etiology
Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
Neurology
Pharmacology. Drug treatments
Prevalence
Risk Factors
Spouses - statistics & numerical data
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Summary:Conjugal multiple sclerosis (MS) is a rare form of MS in which both spouses are affected, and at least one is affected after marriage. Among 1606 definite MS patients, 1076 were in marital relationship, among whom we identified six conjugal pairs, giving the conjugal rate of 0.5%. This rate is 12.5 times higher than the estimated risk of MS for the general population (0.04%). The observed conjugal rate suggests an increased risk of developing MS for MS patients' spouses, this could be due to transmission or, more likely, to the same environmental factors shared in adult life. Multiple Sclerosis 2007; 13: 673-675. http://msj.sagepub.com
ISSN:1352-4585
1477-0970
DOI:10.1177/1352458506072092