When to stress patients after coronary artery bypass surgery? Risk stratification in patients early and late post-CABG using stress myocardial perfusion SPECT: implications of appropriate clinical strategies

The study compared the prognostic significance of myocardial perfusion single-photon emission computed tomography (SPECT) (MPS) in patients early and late after coronary artery bypass graft surgery (CABG). The long-term effectiveness of CABG is limited by graft stenosis. The greatest incidence of gr...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2001-01, Vol.37 (1), p.144-152
Main Authors: Zellweger, M J, Lewin, H C, Lai, S, Dubois, E A, Friedman, J D, Germano, G, Kang, X, Sharir, T, Berman, D S
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Coronary Artery Bypass
Exercise Test
Female
Graft Occlusion, Vascular - diagnostic imaging
Graft Occlusion, Vascular - mortality
Humans
Male
Middle Aged
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - mortality
Prognosis
Risk Assessment
Survival Rate
Tomography, Emission-Computed, Single-Photon
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Summary:The study compared the prognostic significance of myocardial perfusion single-photon emission computed tomography (SPECT) (MPS) in patients early and late after coronary artery bypass graft surgery (CABG). The long-term effectiveness of CABG is limited by graft stenosis. The greatest incidence of graft occlusion occurs between five and eight years after surgery. However, little is known regarding the appropriate time to stress patients post-CABG with respect to risk stratification. We identified 1,765 patients, who underwent MPS 7.1 +/- 5.0 years post-CABG. All patients underwent rest T1-201/stress Tc-99m sestamibi MPS and were followed up > or =1 year after testing. Patients with early CABG or PTCA (5 years post-CABG may benefit from testing.
ISSN:0735-1097
DOI:10.1016/s0735-1097(00)01104-9