Timing of stenting of symptomatic carotid stenosis is predictive of 30-day outcome

For patients with symptomatic carotid stenosis, benefit from carotid artery stenting (CAS) highly depends on the 30‐day stroke and death rates. Identification of predictors of unfavourable outcome would help guide the patient selection. We analysed the influence of clinical and angiographic factors...

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Bibliographic Details
Published in:European journal of neurology 2007-06, Vol.14 (6), p.672-678
Main Authors: Topakian, R., Strasak, A. M., Sonnberger, M., Haring, H.-P., Nussbaumer, K., Trenkler, J., Aichner, F. T.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
angioplasty
Angioplasty - methods
Carotid Artery Diseases - diagnosis
Carotid Artery Diseases - mortality
carotid stenosis
Cohort Studies
complications
Female
Humans
Male
Middle Aged
Outcome Assessment (Health Care)
Predictive Value of Tests
Regression Analysis
Retrospective Studies
risk factors
stents
Stents - adverse effects
stroke
Stroke - diagnosis
Stroke - mortality
Stroke - surgery
Time Factors
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Summary:For patients with symptomatic carotid stenosis, benefit from carotid artery stenting (CAS) highly depends on the 30‐day stroke and death rates. Identification of predictors of unfavourable outcome would help guide the patient selection. We analysed the influence of clinical and angiographic factors on the 30‐day outcomes of 77 consecutive patients who underwent CAS for ≥60% symptomatic carotid stenosis within 180 days of transient ischaemic attack or moderate stroke (modified Rankin Scale score ≤3). The 30‐day composite end‐point for stroke (7.8%) and death of any cause (1.3%) was 9.1%. Patients with complicated CAS were older than patients with uncomplicated CAS (mean age 75.1 ± 8.2 vs. 65.9 ± 9.5 years, P = 0.015) and underwent stenting significantly earlier after the qualifying event: median delay 1.5 weeks (range: 0.2–3.0) vs. 3.2 weeks (range: 0.5–26), P = 0.004. In multivariate logistic regression analyses, age [odds ratio (OR) = 1.148; 95% confidence interval (CI): 1.011–1.304 and P = 0.033] and delay of treatment
ISSN:1351-5101
1468-1331
1471-0552
DOI:10.1111/j.1468-1331.2007.01815.x