Serum profiles of granulocyte-macrophage colony-stimulating factor and C-C chemokines in hypertensive patients with or without significant hyperlipidemia

The present study investigates the differences in serum activity of granulocyte-macrophage colony-stimulating factor, macrophage chemoattractant protein-1, and macrophage inflammatory protein-1alpha between hypertensive patients with and without significant hyperlipidemia before receiving any medica...

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Bibliographic Details
Published in:The American journal of cardiology 2000-03, Vol.85 (6), p.777-779
Main Authors: Parissis, John T, Venetsanou, Koula F, Kalantzi, Maria V, Mentzikof, Demetrios D, Karas, Spilios M
Format: Article
Language:English
Subjects:
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Cardiology
Cardiology. Vascular system
Case-Control Studies
Chemokine CCL2 - blood
Chemokine CCL4
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Female
Granulocyte-Macrophage Colony-Stimulating Factor - blood
Humans
Hyperlipidemias - blood
Hyperlipidemias - complications
Hypertension
Hypertension - blood
Hypertension - complications
Macrophage Inflammatory Proteins - blood
Male
Medical sciences
Middle Aged
Proteins
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Summary:The present study investigates the differences in serum activity of granulocyte-macrophage colony-stimulating factor, macrophage chemoattractant protein-1, and macrophage inflammatory protein-1alpha between hypertensive patients with and without significant hyperlipidemia before receiving any medical treatment. The serum activity of the studied inflammatory factors is more elevated in hypertensive patients with significant hyperlipidemia and may be associated with atherosclerotic inflammatory process induced by the coexistence of 2 major cardiovascular risk factors.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(99)00862-0