Cryptococcal Immune Reconstitution Inflammatory Syndrome following Alemtuzumab Therapy

Alemtuzumab is a lymphocyte ablative agent that may cause susceptibility to severe opportunistic infections similar to those seen in AIDS. Pathogen-specific immune reconstitution syndromes can complicate antiretroviral therapy and immune recovery in HIV-infected patients. We present the first report...

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Bibliographic Details

Published in:	Clinical infectious diseases 2007-06, Vol.44 (12), p.e115-e117
Main Authors:	Ingram, Paul R., Howman, Rebecca, Leahy, Michael F., Dyer, John R.
Format:	Article
Language:	eng
Subjects:	Alemtuzumab Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal, Humanized Antibodies, Neoplasm - adverse effects Antineoplastic Agents - adverse effects Cryptococcus Cryptococcus neoformans - immunology Cryptococcus neoformans - pathogenicity Human immunodeficiency virus Humans Immune System Diseases - immunology Immune System Diseases - microbiology Leukemia, Prolymphocytic - complications Leukemia, Prolymphocytic - drug therapy Leukemia, Prolymphocytic - immunology Leukemia, T-Cell - complications Leukemia, T-Cell - drug therapy Leukemia, T-Cell - immunology Male Middle Aged Salvage Therapy - adverse effects Syndrome
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