Usefulness of Multidetector Spiral Computed Tomography According to Age and Gender for Diagnosis of Acute Pulmonary Embolism

Data from the Prospective Investigation of Pulmonary Embolism Diagnosis II (PIOPED II) were evaluated to test the hypothesis that the performance of multidetector computed tomographic (CT) pulmonary angiography and CT venography is independent of a patient’s age and gender. In 773 patients with adeq...

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Bibliographic Details
Published in:The American journal of cardiology 2007-05, Vol.99 (9), p.1303-1305
Main Authors: Stein, Paul D., MD, Beemath, Afzal, MD, Quinn, Deborah A., MD, Olson, Ronald E., PhD, Goodman, Lawrence R., MD, Gottschalk, Alexander, MD, Hales, Charles A., MD, Hull, Russell D., MBBS, MSc, Leeper, Kenneth V., MD, Sostman, H. Dirk, MD, Weg, John G., MD, Woodard, Pamela K., MD
Format: Article
Language:English
Subjects:
Acute Disease
Adolescent
Adult
Age
Age Factors
Aged
Aged, 80 and over
Angiography
Cardiovascular
Cardiovascular disease
Female
Gender
Humans
Male
Medical diagnosis
Medical imaging
Middle Aged
Prospective Studies
Pulmonary Embolism - diagnostic imaging
Reproducibility of Results
Sensitivity and Specificity
Sex Factors
Tomography, Spiral Computed
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Summary:Data from the Prospective Investigation of Pulmonary Embolism Diagnosis II (PIOPED II) were evaluated to test the hypothesis that the performance of multidetector computed tomographic (CT) pulmonary angiography and CT venography is independent of a patient’s age and gender. In 773 patients with adequate CT pulmonary angiography and 737 patients with adequate CT pulmonary angiography and CT venography, the sensitivity and specificity for pulmonary embolism for groups of patients aged 18 to 59, 60 to 79, and 80 to 99 years did not differ to a statistically significant extent, nor were there significant differences according to gender. Overall, however, the specificity of CT pulmonary angiography was somewhat greater in women, but in men and women, it was ≥93%. In conclusion, the results indicate that multidetector CT pulmonary angiography and CT pulmonary angiography and CT venography may be used with various diagnostic strategies in adults of all ages and both genders.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2006.12.051