Clinical aspects and prognosis of brugada syndrome in children

Brugada syndrome is an arrhythmogenic disease characterized by an ECG pattern of ST-segment elevation in the right precordial leads and augmented risk of sudden cardiac death. Little is known about the clinical presentation and prognosis of this disease in children. Thirty children affected by Bruga...

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Published in:Circulation (New York, N.Y.) N.Y.), 2007-04, Vol.115 (15), p.2042-2048
Main Authors: PROBST, Vincent, DENJOY, Isabelle, LUPOGLAZOFF, Jean-Marc, MABO, Philippe, VELTMANN, Christian, JESEL, Laurence, CHEVALIER, Philippe, CLUR, Sally-Ann B, HAISSAGUERRE, Michel, WOLPERT, Christian, LE MAREC, Hervé, WILDE, Arthur A. M, MEREGALLI, Paola G, AMIRAULT, Jean-Christophe, SACHER, Frédéric, MANSOURATI, Jacques, BABUTY, Dominique, VILLAIN, Elisabeth, VICTOR, Jacques, SCHOTT, Jean-Jacques
Format: Article
Language:English
Subjects:
Adolescent
Anti-Arrhythmia Agents - therapeutic use
Biological and medical sciences
Blood and lymphatic vessels
Brugada Syndrome - complications
Brugada Syndrome - diagnosis
Brugada Syndrome - physiopathology
Cardiology. Vascular system
Child
Child, Preschool
Death, Sudden, Cardiac - etiology
Defibrillators, Implantable
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Electrocardiography
Female
Follow-Up Studies
Genes, Dominant
Humans
Infant
Injuries of the limb. Injuries of the spine
Male
Medical sciences
Muscle Proteins - genetics
NAV1.5 Voltage-Gated Sodium Channel
Prognosis
Quinidine - therapeutic use
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Sodium Channel Blockers
Sodium Channels - genetics
Syncope - etiology
Tachycardia, Supraventricular - diagnosis
Tachycardia, Supraventricular - etiology
Traumas. Diseases due to physical agents
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Description
Summary:Brugada syndrome is an arrhythmogenic disease characterized by an ECG pattern of ST-segment elevation in the right precordial leads and augmented risk of sudden cardiac death. Little is known about the clinical presentation and prognosis of this disease in children. Thirty children affected by Brugada syndrome who were
ISSN:0009-7322
1524-4539
DOI:10.1161/CIRCULATIONAHA.106.664219