Performance of Conventional Echocardiographic Parameters and Myocardial Measurements in the Sequential Evaluation of Left Ventricular Function

Echocardiography is frequently used for sequential evaluation of left ventricular (LV) function, although the reproducibility of such conventional measurements as LV ejection fraction (EF) have been questioned. The utility of such newer measurements as tissue Doppler imaging and left atrial (LA) siz...

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Bibliographic Details
Published in:The American journal of cardiology 2008-03, Vol.101 (5), p.706-711
Main Authors: Hare, James L., MBBS, Brown, Joseph K., BS, Marwick, Thomas H., MBBS, PhD
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood Flow Velocity - physiology
Cardiology
Cardiology. Vascular system
Cardiovascular
Cardiovascular system
Diastole - physiology
Female
Heart
Heart Atria - diagnostic imaging
Heart Atria - physiopathology
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Measurement
Medical procedures
Medical sciences
Middle Aged
Mitral Valve - diagnostic imaging
Mitral Valve - physiopathology
Severity of Illness Index
Stroke Volume - physiology
Ultrasonic imaging
Ultrasonic investigative techniques
Ultrasonography
Ventricular Dysfunction, Left - diagnostic imaging
Ventricular Dysfunction, Left - physiopathology
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Summary:Echocardiography is frequently used for sequential evaluation of left ventricular (LV) function, although the reproducibility of such conventional measurements as LV ejection fraction (EF) have been questioned. The utility of such newer measurements as tissue Doppler imaging and left atrial (LA) size in serial clinical testing are undefined. The magnitude and clinical relevance of changes in conventional and new measurements of LV function were investigated and compared in 346 consecutive patients undergoing sequential echocardiography. Change in LA area, LVEF, tissue E velocity (Em), and transmitral E to Em ratio (E/Em) were compared over 304 ± 239 days. Changes within and between parameters (after mean correction to make measurements comparable) were assessed in groups designated as stable (n = 144) or unstable (n = 202) according to clinical progress. A single observer remeasured these parameters in stable patients individually and with paired studies side by side. Significant variability was seen in all measurements, with change in LVEF the only parameter differing between stable and unstable groups (6.4 ± 8.9% vs 9.4 ± 5.4%; p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2007.10.037