The predictors of central and obstructive sleep apnoea in haemodialysis patients

Background. Sleep apnoea (SA) is often observed in haemodialysis patients, but there have been few studies on types of SA and their predictors. We therefore investigated the prevalence and types of SA and the associations between types of SA and clinical factors in haemodialysis patients. Methods. W...

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Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 2007-04, Vol.22 (4), p.1190-1197
Main Authors: Tada, Takeshi, Kusano, Kengo Fukushima, Ogawa, Aiko, Iwasaki, Jun, Sakuragi, Satoru, Kusano, Isao, Takatsu, Seiko, Miyazaki, Masashi, Ohe, Tohru
Format: Article
Language:English
Subjects:
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Bicarbonates - blood
Biological and medical sciences
Blood Urea Nitrogen
Body Mass Index
Carbon Dioxide - metabolism
central sleep apnoea
Creatinine - blood
Diagnosis, Differential
Emergency and intensive care: renal failure. Dialysis management
Female
Glomerulonephritis
haemodialysis
Humans
Intensive care medicine
Kidney Failure, Chronic - therapy
Male
Medical sciences
Middle Aged
Multivariate Analysis
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
obstructive sleep apnoea
Oxygen - metabolism
Predictive Value of Tests
Prevalence
Renal Dialysis - adverse effects
Risk Factors
Sleep Apnea, Central - blood
Sleep Apnea, Central - complications
Sleep Apnea, Central - etiology
Sleep Apnea, Obstructive - blood
Sleep Apnea, Obstructive - complications
Sleep Apnea, Obstructive - epidemiology
sleep apnoea syndrome
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
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Summary:Background. Sleep apnoea (SA) is often observed in haemodialysis patients, but there have been few studies on types of SA and their predictors. We therefore investigated the prevalence and types of SA and the associations between types of SA and clinical factors in haemodialysis patients. Methods. We initially examined nocturnal oxygen desaturation index (ODI) (desaturation of >4%/events per hour) in 119 haemodialysis patients (68 males, mean age of 61.4 years). Patients with ODI of more than five were diagnosed as having SA. Then, 30 patients underwent polysomnography and we measured Apnoea–hypopnoea index (AHI), which was calculated as the number of apnoeas plus hypopnoeas per hour of sleep. Clinical characteristics were examined in all patients. Results. Forty-one (34.5%) of the 119 patients had SA. Twenty-seven (22.7%) of the 119 patients had SA with subjective symptoms such as daytime somnolence and snoring. There was a significant difference between body mass index (BMI) in patients with SA and that in patients without SA (22.5 vs 19.8 kg/m2, P 
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfl748