Large Metastatic Lymph Node Size, Especially More Than 2 cm: Independent Predictor of Poor Prognosis in Node-Positive Gastric Carcinoma

The presence of metastatic lymph nodes (MLNs) is the most important prognostic factor for gastric carcinoma, with the number of MLNs thought to be predictive of the prognosis. However, there have been long-standing debates on how to classify node-positive patients into prognostic groups appropriatel...

Full description

Saved in:
Bibliographic Details
Published in:World journal of surgery 2008-02, Vol.32 (2), p.262-n/a
Main Authors: Cheong, O., Oh, S. T., Kim, B. S., Yook, J. H., Kim, J. H., Im, J. T., Park, G. C.
Format: Article
Language:English
Subjects:
Abdominal Surgery
Adult
Aged
Biological and medical sciences
Carcinoma - mortality
Carcinoma - secondary
Carcinoma - surgery
Cardiac Surgery
Cohort Studies
Female
Gastrectomy
Gastric Carcinoma
Gastroenterology. Liver. Pancreas. Abdomen
General aspects
General Surgery
Histologic Classification
Humans
Lymph Node Excision
Lymph Nodes - pathology
Male
Medical sciences
Medicine
Medicine & Public Health
Middle Aged
Mucinous Adenocarcinoma
Neoplasm Staging
Predictive Value of Tests
Prognostic Group
Retrospective Studies
Stomach Neoplasms - mortality
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Surgery
Survival Rate
Thoracic Surgery
Tumor Depth
Tumors
Vascular Surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The presence of metastatic lymph nodes (MLNs) is the most important prognostic factor for gastric carcinoma, with the number of MLNs thought to be predictive of the prognosis. However, there have been long-standing debates on how to classify node-positive patients into prognostic groups appropriately. Recent findings in patients with colon and esophageal cancer have suggested that MLN size, more than MLN number, is an important prognostic factor; but less is known about the impact of MLN size on the prognosis of patients with gastric carcinoma. We therefore assessed the prognostic impact of large MLNs, especially those ≥2 cm, in patients with gastric carcinoma. A total of 1190 patients who underwent curative resection for gastric carcinoma between 2001 and 2003 and had lymph node metastases were divided into two groups according to the size of the largest MLN: ≥2 cm ( n = 51) vs.
ISSN:0364-2313
1432-2323
DOI:10.1007/s00268-007-9158-4