Characterization of focal right atrial appendage tachycardia

Aims Though right atrial appendage tachycardia (RAAT) has been described, no studies to date have focused on its clinical characterization. The aim of the present study was to analyze its clinical, electrocardiographic (ECG), and electrophysiologic (EP) characteristics and the results of radiofreque...

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Bibliographic Details
Published in:Europace (London, England) England), 2008-01, Vol.10 (1), p.105-109
Main Authors: Freixa, Xavier, Berruezo, Antonio, Mont, Lluís, Magnani, Santiago, Benito, Begoña, Tolosana, Jose María, Perafan, Pablo, Tamborero, David, Brugada, Josep
Format: Article
Language:English
Subjects:
Adult
Aged
Atrial Appendage - physiopathology
Atrial Appendage - surgery
Catheter Ablation
Dyspnea - etiology
Dyspnea - physiopathology
Electrocardiography
Electrophysiologic Techniques, Cardiac
Female
Follow-Up Studies
Humans
Longitudinal Studies
Male
Middle Aged
Predictive Value of Tests
Sensitivity and Specificity
Tachycardia, Ectopic Atrial - complications
Tachycardia, Ectopic Atrial - physiopathology
Tachycardia, Ectopic Atrial - surgery
Treatment Outcome
Ventricular Dysfunction, Left - etiology
Ventricular Dysfunction, Left - physiopathology
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Summary:Aims Though right atrial appendage tachycardia (RAAT) has been described, no studies to date have focused on its clinical characterization. The aim of the present study was to analyze its clinical, electrocardiographic (ECG), and electrophysiologic (EP) characteristics and the results of radiofrequency ablation (RFA) in RAAT. Methods and results Out of 186 consecutive patients undergoing RFA for AT, 15 (8%) had focal RAAT. Mapping was performed using conventional catheters or a 3D electroanatomic mapping system. Patients with RAAT were more likely to be male (66 vs. 38%; P= 0.013) and younger (32 ± 12.6 vs. 55 ± 13.2 years; P < 0.001) than patients with AT originating elsewhere. They were also more likely to have dyspnea (27 vs. 7.6%; P = 0.03), incessant tachycardia (53 vs. 16%; P < 0.001), and left ventricular systolic dysfunction (27 vs. 5%; P = 0.018). RFA was effective in all patients (100 vs. 75%; P = 0.022) and no recurrences (0 vs. 8%; P = 0.31) were observed during a mean follow-up of 37 ± 36 months. A specific ECG pattern was identified, consisting of negative P-waves in leads V1-V2 and a transition to positivity in the rest of the precordial leads. This ECG pattern correctly identified RAAT with a sensitivity of 100%, a specificity of 98%, a positive predictive value of 88%, and a negative predictive value of 100%. Conclusion Right atrial appendage tachycardia is more prevalent in young male patients and is commonly associated with tachycardiomyopathy. RFA is effective over long-term follow-up. A characteristic ECG pattern identifies RAAT with a very high sensitivity and specificity.
ISSN:1099-5129
1532-2092
DOI:10.1093/europace/eum264