Relation of Low Hemoglobin and Anemia to Morbidity and Mortality in Patients Hospitalized With Heart Failure (Insight from the OPTIMIZE-HF Registry)

Anemia in heart failure (HF) is increasingly recognized and treated, but little is known about the prevalence and its relation to outcomes in patients hospitalized for decompensated HF in a situation of both reduced and preserved systolic function. We hypothesized that lower hemoglobin is correlated...

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Bibliographic Details
Published in:The American journal of cardiology 2008-01, Vol.101 (2), p.223-230
Main Authors: Young, James B., MD, Abraham, William T., MD, Albert, Nancy M., RN, PhD, Gattis Stough, Wendy, PharmD, Gheorghiade, Mihai, MD, Greenberg, Barry H., MD, O’Connor, Christopher M., MD, She, Lilin, PhD, Sun, Jie Lena, MS, Yancy, Clyde W., MD, Fonarow, Gregg C., MD
Format: Article
Language:English
Subjects:
ACE inhibitors
Anemia - blood
Anemia - complications
Anemia - mortality
Anemias. Hemoglobinopathies
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Cardiovascular
Diseases of red blood cells
Female
Heart
Heart failure
Heart Failure - blood
Heart Failure - complications
Heart Failure - mortality
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Hematologic and hematopoietic diseases
Hemoglobin
Hemoglobins - metabolism
Hospital Mortality
Humans
Length of Stay - statistics & numerical data
Male
Medical sciences
Middle Aged
Mortality
Prevalence
Prospective Studies
Quality Assurance, Health Care
Registries
Survival Analysis
United States - epidemiology
White people
Women
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Summary:Anemia in heart failure (HF) is increasingly recognized and treated, but little is known about the prevalence and its relation to outcomes in patients hospitalized for decompensated HF in a situation of both reduced and preserved systolic function. We hypothesized that lower hemoglobin is correlated with death during hospitalization and 60 to 90 days postdischarge in patients with HF. The Organized Program to Initiate Lifesaving Treatment in Patients with Heart Failure is a registry and performance improvement program for hospitalized patients with HF. Study cohorts were defined by admission hemoglobin quartile. Data from 48,612 patients at 259 hospitals showed that half of the total cohort had low hemoglobin (
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2007.07.067