Suppression of alcohol consumption in C57Bl/6 mice after intranasal administration of antiserotonin antibodies

Experiments on C57Bl/6 mice under conditions of free choice between alcohol and water for 10 months showed that intranasal administration with antiserotonin antibodies in doses of 30 and 15 microg/kg for 2 week decreased alcohol consumption over 1 month after treatment.

Saved in:
Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2005-12, Vol.140 (6), p.687-689
Main Authors: Davydova, T V, Fomina, V G, Basharova, L A, Fedenko, A M
Format: Article
Language:English
Subjects:
Administration, Intranasal
Alcohol Deterrents - pharmacology
Alcohol Drinking
Animals
Antibodies - pharmacology
Behavior, Animal
gamma-Globulins - metabolism
Male
Mice
Mice, Inbred C57BL
Serotonin - immunology
Time Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Experiments on C57Bl/6 mice under conditions of free choice between alcohol and water for 10 months showed that intranasal administration with antiserotonin antibodies in doses of 30 and 15 microg/kg for 2 week decreased alcohol consumption over 1 month after treatment.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-006-0054-y