International Scientific Committee of Radionuclides in Nephrourology (ISCORN) Consensus on Renal Transit Time Measurements

This report is the conclusion of the international consensus committee on renal transit time (subcommittee of the International Scientific Committee of Radionuclides in Nephrourology) and provides recommendations on measurement, normal values, and analysis of clinical utility. Transit time is the ti...

Full description

Saved in:
Bibliographic Details
Published in:Seminars in nuclear medicine 2008, Vol.38 (1), p.82-102
Main Authors: Durand, Emmanuel, MD, PhD, Blaufox, M. Donald, MD, PhD, Britton, Keith E., MD, MSc, FRCR, FRCP, Carlsen, Ove, MSc, PhD, Cosgriff, Philip, MSc, Fine, Eugene, MD, MS, Fleming, John, PhD, Nimmon, Cyril, BSc, Piepsz, Amy, MD, PhD, Prigent, Alain, MD, PhD, Šamal, Martin, MD, PhD
Format: Article
Language:English
Subjects:
Diagnosis, Computer-Assisted - standards
Humans
Internationality
Kidney Diseases - diagnosis
Nephrology - standards
Practice Guidelines as Topic
Practice Patterns, Physicians' - standards
Radioisotope Renography - standards
Radiology
Urology - standards
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This report is the conclusion of the international consensus committee on renal transit time (subcommittee of the International Scientific Committee of Radionuclides in Nephrourology) and provides recommendations on measurement, normal values, and analysis of clinical utility. Transit time is the time that a tracer remains within the kidney or within a part of the kidney (eg, parenchymal transit time). It can be obtained from a dynamic renogram and a vascular input acquired in standardized conditions by a deconvolution process. Alternatively to transit time measurement, simpler indices were proposed, such as time of maximum, normalized residual activity or renal output efficiency. Transit time has been mainly used in urinary obstruction, renal artery stenosis, or renovascular hypertension and renal transplant. Despite a large amount of published data on obstruction, only the value of normal transit is established. The value of delayed transit remains controversial, probably due to lack of a gold standard for obstruction. Transit time measurements are useful to diagnose renovascular hypertension, as are some of the simpler indices. The committee recommends further collaborative trials.
ISSN:0001-2998
1558-4623
DOI:10.1053/j.semnuclmed.2007.09.009