Cardiac Outcome up to 15 Years After the Arterial Switch Operation

Aims To assess the cardiac outcome and risk factors for mortality of infants following the arterial switch operation (ASO). Methods A single-centre retrospective review was conducted. Preoperative assessment, operative management and outcome was detailed for 244 patients undergoing the ASO at Green...

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Bibliographic Details
Published in:Heart, lung & circulation lung & circulation, 2008-02, Vol.17 (1), p.48-53
Main Authors: Wong, Sharon H., FRACP, Finucane, Kirsten, FRACS, Kerr, Alan R., FRACS, O’Donnell, Clare, FRACP, West, Teena, MSc, Gentles, Thomas L., FRACP
Format: Article
Language:English
Subjects:
Analysis of Variance
Arterial switch operation
Cardiac Surgical Procedures - adverse effects
Cardiac Surgical Procedures - methods
Cardiovascular
Cause of Death
Cohort Studies
Double Outlet Right Ventricle - diagnosis
Double Outlet Right Ventricle - mortality
Double Outlet Right Ventricle - surgery
Female
Follow-Up Studies
Hospital Mortality - trends
Humans
Infant, Newborn
Male
Mortality
Probability
Retrospective Studies
Risk Assessment
Survival Analysis
Time Factors
Transposition of Great Vessels - diagnosis
Transposition of Great Vessels - mortality
Transposition of Great Vessels - surgery
Vascular Surgical Procedures - adverse effects
Vascular Surgical Procedures - methods
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Summary:Aims To assess the cardiac outcome and risk factors for mortality of infants following the arterial switch operation (ASO). Methods A single-centre retrospective review was conducted. Preoperative assessment, operative management and outcome was detailed for 244 patients undergoing the ASO at Green Lane Hospital for transposition of the great arteries (TGA) or double outlet right ventricle. Results The postoperative survival at 1, 5 and 15 years was 85%, 84% and 83%, respectively. The calendar year of ASO and the presence of a ventricular septal defect (VSD) were the primary predictors of early mortality. Late mortality was associated with a side-by-side configuration of the great arteries. Re-intervention following ASO was more common in patients with prolonged cardiopulmonary bypass time. Conclusions Low early and late morbidity and mortality can be obtained in infants with TGA or double outlet right ventricle by definitive repair utilising the ASO.
ISSN:1443-9506
1444-2892
DOI:10.1016/j.hlc.2007.06.523