Soy protein for the prevention and treatment of children with cow-milk allergy

Soy-protein formulas are widely used for feeding babies with cow-milk allergy. When they first were marketed, these formulas were the only available cow-milk substitute and they ensured a normal life for many children who were affected by the large spectrum of clinical manifestations of cow-milk all...

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Bibliographic Details
Published in:The American journal of clinical nutrition 1998-12, Vol.68 (6), p.1447S-1452S
Main Authors: BUSINCO, L, BRUNO, G, GIAMPIETRO, P. G
Format: Article
Language:English
Subjects:
Allergic diseases
Allergies
Animals
Biological and medical sciences
Children & youth
Digestive allergic diseases
Humans
Immunopathology
Infant
Infant Food - adverse effects
Infant, Newborn
Medical sciences
Milk
Milk - adverse effects
Milk Hypersensitivity - diet therapy
Milk Hypersensitivity - immunology
Milk Hypersensitivity - prevention & control
Preventive medicine
Proteins
Soybean Proteins - adverse effects
Soybean Proteins - therapeutic use
Soybeans
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Summary:Soy-protein formulas are widely used for feeding babies with cow-milk allergy. When they first were marketed, these formulas were the only available cow-milk substitute and they ensured a normal life for many children who were affected by the large spectrum of clinical manifestations of cow-milk allergy. Soy-protein formulas were also given to allergy-prone infants for the prevention of atopic diseases when breast milk was not available. Several researchers studied the prevalence of soy sensitization in allergic disease. Few studies used a challenge test for the diagnosis of soy allergy, even those in patients in whom soy allergy was suspected. In most studies the diagnosis of soy allergy was based on anecdotal case histories reported by parents and was not substantiated by scientific diagnostic criteria: no challenge test to soy was made nor were data available on specific immunoglobulin E to soy. In this paper we critically reviewed literature on the safety of feeding soy-protein formulas to babies with cow-milk allergy as well as on the prevention of cow-milk allergy.
ISSN:0002-9165
1938-3207
DOI:10.1093/ajcn/68.6.1447S