Effect of hindlimb unloading on interlimb coordination during treadmill locomotion in the rat

Effects of hindlimb unloading on interlimb coordination were examined in adult rats walking on a treadmill at moderate speed. In the first group of animals, the electromyographic activity (EMG) of soleus muscle of both hindlimbs was recorded after 7 and 14 days of unloading. In the second group, the...

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Bibliographic Details
Published in:European journal of applied physiology 1998-11, Vol.78 (6), p.509-515
Main Authors: Canu, M H, Falempin, M
Format: Article
Language:English
Subjects:
Animals
Ankle Joint - physiology
Electromyography
Gait - physiology
Hindlimb - physiology
Hypokinesia - physiopathology
Locomotion - physiology
Male
Muscle, Skeletal - physiology
Periodicity
Proprioception - physiology
Rats
Rats, Wistar
Reaction Time - physiology
Space life sciences
Weightlessness
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Summary:Effects of hindlimb unloading on interlimb coordination were examined in adult rats walking on a treadmill at moderate speed. In the first group of animals, the electromyographic activity (EMG) of soleus muscle of both hindlimbs was recorded after 7 and 14 days of unloading. In the second group, the EMG was recorded daily until the 14th day of unloading. The general organization of locomotion was preserved in the two groups whatever the duration of the unloading. The step cycles of the two hindlimbs were always strictly alternating. However, the locomotor pattern was very irregular. A lateral instability was observed. It was accompanied by an abduction of the hindlimbs, and frequent hyperextensions of the ankle when walking. The EMG analysis showed an increase in step cycle duration and in coactivation duration of the soleus muscles (i.e. in the double stance duration). In the rats recorded daily, mean EMG was dramatically reduced the 1st day of unloading, suggesting a decrease in the neural drive. Taken together, these data indicate that 14 days of hindlimb unloading can alter the neuromuscular pattern during locomotion. It is proposed that these changes are related to changes in the peripheral sensory information.
ISSN:0301-5548
1439-6319
1432-1025
1439-6327
DOI:10.1007/s004210050453