Hyperthyroidism: A Novel Feature of the Tubulointerstitial Nephritis and Uveitis Syndrome

Tubulointerstitial nephritis and uveitis syndrome presents with either renal or ocular manifestations, and associated weight loss. We report two adolescents with transient hyperthyroidism early in the course of the syndrome. Hyperthyroidism may represent an unrecognized feature of the disorder and p...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1999-08, Vol.104 (2), p.314-317
Main Authors: Paul, Elahna, Van Why, Scott, Carpenter, Thomas O
Format: Article
Language:English
Subjects:
Adolescent
Biological and medical sciences
Case studies
Causes of
Children & youth
Complications and side effects
Disease
Endocrinopathies
Female
Humans
Hyperthyroidism
Hyperthyroidism - etiology
Immune system
Kidney diseases
Male
Medical sciences
Nephritis, Interstitial - complications
Nephritis, Interstitial - physiopathology
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Pediatrics
Syndrome
Thyroid gland
Thyroid. Thyroid axis (diseases)
Uveitis - complications
Uveitis - physiopathology
Weight Loss
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Summary:Tubulointerstitial nephritis and uveitis syndrome presents with either renal or ocular manifestations, and associated weight loss. We report two adolescents with transient hyperthyroidism early in the course of the syndrome. Hyperthyroidism may represent an unrecognized feature of the disorder and potentially contributes to the accompanying weight loss. Thyroid function should be evaluated in patients with tubulointerstitial nephritis and uveitis syndrome and symptomatic therapy provided when necessary.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.104.2.314