A Polyisoprenylated Benzophenone from Cuban Propolis

A novel polyisoprenylated benzophenone (1) has been isolated from an ethanol extract of Cuban propolis. Its structure has been determined using high-field 2D NMR techniques. Compound 1 showed significant antimicrobial and antifungal activity against a variety of bacteria and yeasts.

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 1999-07, Vol.62 (7), p.1013-1015
Main Authors: Rubio, O. Cuesta, Cuellar, Rojas, N, Castro, Herman Velez, Rastrelli, Luca, Aquino, Rita
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents
Anti-Infective Agents - chemistry
Anti-Infective Agents - isolation & purification
antibacterial properties
Antifungal Agents - chemistry
Antifungal Agents - isolation & purification
antifungal properties
Apis mellifera
Bacteria - drug effects
benzophenone
Benzophenones - chemistry
Benzophenones - isolation & purification
Biological and medical sciences
chemical composition
chemical structure
Chromatography, High Pressure Liquid
Clusia
clusia minor
clusia rosea
Cuba
flowers
General pharmacology
isoprenoids
ketones
Magnetic Resonance Spectroscopy
Medical sciences
Microbial Sensitivity Tests
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
propolis
Propolis - chemistry
resins
spectral analysis
Spectrophotometry, Infrared
Yeasts - drug effects
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Description
Summary:A novel polyisoprenylated benzophenone (1) has been isolated from an ethanol extract of Cuban propolis. Its structure has been determined using high-field 2D NMR techniques. Compound 1 showed significant antimicrobial and antifungal activity against a variety of bacteria and yeasts.
ISSN:0163-3864
1520-6025
DOI:10.1021/np980339n