Relation of Epicardial Adipose Tissue to Coronary Atherosclerosis

Adipose tissue surrounding the coronary arteries has been suggested to induce development of atherosclerosis. We explored the relation between epicardial adipose tissue (EAT) volume and coronary atherosclerosis using multislice computed tomography. The study population consisted of 190 patients who...

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Published in:The American journal of cardiology 2008-12, Vol.102 (12), p.1602-1607
Main Authors: Djaberi, Roxana, MD, Schuijf, Joanne D., PhD, van Werkhoven, Jacob M, Nucifora, Gaetano, MD, Jukema, J. Wouter, MD, PhD, Bax, Jeroen J., MD, PhD
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Language:eng
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Summary:Adipose tissue surrounding the coronary arteries has been suggested to induce development of atherosclerosis. We explored the relation between epicardial adipose tissue (EAT) volume and coronary atherosclerosis using multislice computed tomography. The study population consisted of 190 patients who had undergone multislice computed tomographic coronary angiography. Coronary artery calcium score was assessed. In addition, patients were classified as having (1) no atherosclerosis, (2) nonobstructive atherosclerosis (luminal narrowing 10 had significantly larger average EAT volume (100 ± 40 ml) compared with patients with calcium scores ≤10 (59 ± 27 ml, p 10 were 77% and 70% with a cut-off EAT value of 73 ml. In patients with normal coronaries mean EAT volume (63 ± 31 ml) was significantly smaller than in patients with atherosclerosis (99 ± 40 ml, p
ISSN:0002-9149
1879-1913