Physical activity and mortality in men and women with coronary heart disease: a prospective population-based cohort study in Norway (the HUNT study)

Background Patients with established coronary heart disease (CHD) are encouraged to be physically active to prevent disease progression and to prolong life. The amount and intensity of exercise required for risk reduction in patients with CHD is not yet fully resolved. Design Population-based prospe...

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Bibliographic Details
Published in:European journal of cardiovascular prevention and rehabilitation 2008-12, Vol.15 (6), p.639-645
Main Authors: Moholdt, Trine, Wisløff, Ulrik, Nilsen, Tom Ivar L., Slørdahl, Stig A.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Cohort Studies
Coronary Disease - mortality
Coronary Disease - physiopathology
Disease Progression
Exercise
Female
Humans
Male
Middle Aged
Norway - epidemiology
Proportional Hazards Models
Prospective Studies
Risk Assessment
Risk Reduction Behavior
Time Factors
Young Adult
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Summary:Background Patients with established coronary heart disease (CHD) are encouraged to be physically active to prevent disease progression and to prolong life. The amount and intensity of exercise required for risk reduction in patients with CHD is not yet fully resolved. Design Population-based prospective cohort study with 18 years of follow-up. Methods A linkage between a Norwegian population-based study (Nord-Trøndelag health study) and the Cause of Death Registry at Statistics Norway. Exercise amount and intensity were measured at baseline (1984–1986) in 2137 men and 1367 women with CHD. Results During 18 years of follow-up, 1741 (81.6%) men and 1100 (80.5%) women died. Compared with the reference category (no activity), one weekly exercise session was associated with a lower all-cause mortality, both in men (relative risk 0.80, 95% confidence interval 0.68–0.94) and women (relative risk 0.68, 95% confidence interval 0.55–0.83). This inverse association became stronger with increasing frequency (P ≤ 0.001 for men and women). Those who reported moderate or high-intensity exercise had a somewhat lower risk of death than those who exercised with low intensity. Conclusion Exercise training reduced all-cause and cardiovascular mortality in men and women with CHD. This study adds significantly to the sparse literature regarding prospective data on physical activity, exercise intensity and mortality in CHD patients. Eur J Cardiovasc Prev Rehabil 15:639–645 © 2008 The European Society of Cardiology
ISSN:2047-4873
1741-8267
2047-4881
1741-8275
DOI:10.1097/HJR.0b013e3283101671