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Splenic and Hepatic Hemozoin in Mice after Malaria Parasite Clearance
Hemozoin (malaria pigment) is found in many tissues during malaria infections. In mice that have self-cured from Plasmodium yoelii and Plasmodium chabaudi infections, liver hemozoin concentration and total content decreased for 6-9 mo after parasite clearance. However, both spleen hemozoin concentra...
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| Published in: | The Journal of parasitology 1999-06, Vol.85 (3), p.570-573 |
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| Main Authors: | , , |
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| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c432t-37c2f9f980833afe83c02bef967e6beeed02357ce501dc41543a14fa62d20f693 |
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| container_end_page | 573 |
| container_issue | 3 |
| container_start_page | 570 |
| container_title | The Journal of parasitology |
| container_volume | 85 |
| creator | LEVESQUE, M. A SULLIVAN, A. D MESHNICK, S. R |
| description | Hemozoin (malaria pigment) is found in many tissues during malaria infections. In mice that have self-cured from Plasmodium yoelii and Plasmodium chabaudi infections, liver hemozoin concentration and total content decreased for 6-9 mo after parasite clearance. However, both spleen hemozoin concentration and total hemozoin content increased dramatically during this time period. Thus, hemozoin or hemozoin-laden macrophages continue to accumulate in murine spleens for at least several months after malaria parasitemia becomes undetectable. |
| doi_str_mv | 10.2307/3285800 |
| format | article |
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A</creatorcontrib><creatorcontrib>SULLIVAN, A. D</creatorcontrib><creatorcontrib>MESHNICK, S. R</creatorcontrib><title>Splenic and Hepatic Hemozoin in Mice after Malaria Parasite Clearance</title><title>The Journal of parasitology</title><addtitle>J Parasitol</addtitle><description>Hemozoin (malaria pigment) is found in many tissues during malaria infections. In mice that have self-cured from Plasmodium yoelii and Plasmodium chabaudi infections, liver hemozoin concentration and total content decreased for 6-9 mo after parasite clearance. However, both spleen hemozoin concentration and total hemozoin content increased dramatically during this time period. 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R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Splenic and Hepatic Hemozoin in Mice after Malaria Parasite Clearance</atitle><jtitle>The Journal of parasitology</jtitle><addtitle>J Parasitol</addtitle><date>1999-06-01</date><risdate>1999</risdate><volume>85</volume><issue>3</issue><spage>570</spage><epage>573</epage><pages>570-573</pages><issn>0022-3395</issn><eissn>1937-2345</eissn><coden>JOPAA2</coden><notes>ObjectType-Article-2</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-1</notes><notes>content type line 23</notes><notes>ObjectType-Article-1</notes><notes>ObjectType-Feature-2</notes><abstract>Hemozoin (malaria pigment) is found in many tissues during malaria infections. In mice that have self-cured from Plasmodium yoelii and Plasmodium chabaudi infections, liver hemozoin concentration and total content decreased for 6-9 mo after parasite clearance. However, both spleen hemozoin concentration and total hemozoin content increased dramatically during this time period. Thus, hemozoin or hemozoin-laden macrophages continue to accumulate in murine spleens for at least several months after malaria parasitemia becomes undetectable.</abstract><cop>Lawrence, KS</cop><pub>American Society of Parasitologists</pub><pmid>10386458</pmid><doi>10.2307/3285800</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3395 |
| ispartof | The Journal of parasitology, 1999-06, Vol.85 (3), p.570-573 |
| issn | 0022-3395 1937-2345 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69853142 |
| source | JSTOR Archival Journals and Primary Sources Collection |
| subjects | Animals Biological and medical sciences Experimental protozoal diseases and models Hemeproteins - analysis Infections Infectious diseases Liver Liver - chemistry Liver - pathology Macrophages Malaria Malaria - metabolism Male Medical sciences Mice Mice, Inbred ICR Organ Size Parasitemia Parasites Parasitic diseases Parasitology Pigments Pigments, Biological - analysis Plasmodium chabaudi Plasmodium chabaudi - physiology Plasmodium yoelii Plasmodium yoelii - physiology Protozoal diseases Research Notes Spleen Spleen - chemistry Spleen - pathology |
| title | Splenic and Hepatic Hemozoin in Mice after Malaria Parasite Clearance |
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