The metabolic syndrome is related to albuminuria in Type 2 diabetes

Aims  To determine the relationships between metabolic syndrome (MetS), diabetic nephropathy (DN) and renal function in Type 2 diabetes. Methods  In a clinic‐based cohort of 1314 Type 2 diabetic patients (58% male; age 62 ± 10 years), we analysed MetS, detected DN and estimated glomerular filtration...

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Bibliographic Details
Published in:Diabetic medicine 2008-12, Vol.25 (12), p.1412-1418
Main Authors: Bianchi, C., Penno, G., Daniele, G., Russo, E., Giovannitti, M. G., Del Prato, S., Miccoli, R.
Format: Article
Language:English
Subjects:
Aged
Albuminuria - blood
Albuminuria - etiology
Albuminuria - physiopathology
Associated diseases and complications
Biological and medical sciences
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - physiopathology
Diabetes. Impaired glucose tolerance
Diabetic Nephropathies - blood
Diabetic Nephropathies - complications
diabetic nephropathy
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Glomerular Filtration Rate
Humans
Kidney Failure, Chronic - blood
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - physiopathology
Male
Medical sciences
metabolic syndrome
Metabolic Syndrome - blood
Metabolic Syndrome - etiology
Middle Aged
Type 2 diabetes
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vertebrates: endocrinology
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Summary:Aims  To determine the relationships between metabolic syndrome (MetS), diabetic nephropathy (DN) and renal function in Type 2 diabetes. Methods  In a clinic‐based cohort of 1314 Type 2 diabetic patients (58% male; age 62 ± 10 years), we analysed MetS, detected DN and estimated glomerular filtration rate (eGFR). Results  Prevalence of both microalbuminuria and macroalbuminuria were higher in subjects with MetS than in those without. Prevalence of DN (microalbuminuria and macroalbuminuria) increased with the number of MetS components. eGFR was lower in subjects with MetS than in those without (87 ± 23 vs. 92 ± 20 ml/min per 1.73 m2; P 
ISSN:0742-3071
1464-5491
DOI:10.1111/j.1464-5491.2008.02603.x