Azadirachtin Story

Azadirachtin has been the subject of intensive research within the scientific community ever since its isolation from the neem tree in 1968. There are now over 1000 publications relating to this natural product which cover all aspects of structural, biological and synthetic studies. Herein, we descr...

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Bibliographic Details
Published in:Angewandte Chemie (International ed.) 2008-11, Vol.47 (49), p.9402-9429
Main Authors: Veitch, Gemma E, Boyer, Alistair, Ley, Steven V
Format: Article
Language:English
Subjects:
antifeedants
Azadirachta - chemistry
Claisen rearrangement
epoxidation
Limonins - chemical synthesis
Limonins - chemistry
Limonins - isolation & purification
natural products
radical cyclization
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Summary:Azadirachtin has been the subject of intensive research within the scientific community ever since its isolation from the neem tree in 1968. There are now over 1000 publications relating to this natural product which cover all aspects of structural, biological and synthetic studies. Herein, we describe the worldwide synthesis efforts towards this fascinating molecule.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200802675