Secondary amyloidosis has decreased in patients with inflammatory joint disease in Finland

We studied whether the high incidence of secondary amyloidosis (SA) is a consistent finding in patients with inflammatory joint disease. A total of 4508 biopsies of patients with rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis were studied at the Rheumatism Foundation Hospital du...

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Bibliographic Details
Published in:Clinical rheumatology 1999-01, Vol.18 (2), p.122-123
Main Authors: Laiho, K, Tiitinen, S, Kaarela, K, Helin, H, Isomäki, H
Format: Article
Language:English
Subjects:
Amyloidosis - epidemiology
Amyloidosis - etiology
Arthritis
Arthritis, Juvenile - complications
Arthritis, Psoriatic - complications
Arthritis, Rheumatoid - complications
Finland - epidemiology
Humans
Incidence
Rheumatism
Spondylitis, Ankylosing - complications
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Summary:We studied whether the high incidence of secondary amyloidosis (SA) is a consistent finding in patients with inflammatory joint disease. A total of 4508 biopsies of patients with rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis were studied at the Rheumatism Foundation Hospital during 1987-1997. The results show that the annual number of findings of SA was reduced from 68 to less than 10. We suggest that a change in medication towards more frequent use of cytostatic agents is the reason for the reduction in incidence of SA.
ISSN:0770-3198
1434-9949
DOI:10.1007/s100670050068