Association of abnormal cerebellar activation with motor learning difficulties in dyslexic adults

In addition to their impairments in literacy-related skills, dyslexic children show characteristic difficulties in phonological skill, motor skill, and balance. There is behavioural and biochemical evidence that these difficulties may be attributable to mild cerebellar dysfunction. We wanted to find...

Full description

Saved in:
Bibliographic Details
Published in:The Lancet (British edition) 1999-05, Vol.353 (9165), p.1662-1667
Main Authors: Nicolson, Roderick I, Fawcett, Angela J, Berry, Emma L, Jenkins, I Harri, Dean, Paul, Brooks, David J
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Biological and medical sciences
Brain
Brain - blood supply
Cerebellum - diagnostic imaging
Cerebellum - pathology
Dyslexia
Dyslexia - diagnostic imaging
Dyslexia - pathology
Female
Humans
Language and communication disorders
Learning
Male
Medical research
Medical sciences
Motor Skills
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Radiography
Regional Blood Flow
Tomography, Emission-Computed
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In addition to their impairments in literacy-related skills, dyslexic children show characteristic difficulties in phonological skill, motor skill, and balance. There is behavioural and biochemical evidence that these difficulties may be attributable to mild cerebellar dysfunction. We wanted to find out whether there was abnormal brain activation when dyslexic adults undertook tasks known normally to involve cerebellar activation. Brain activation was monitored by positron emission tomography in matched groups of six dyslexic adults and six control adults as they carried out either a prelearned sequence or learned a novel sequence of finger movements Brain activation was significantly lower (p
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(98)09165-X