PREOPERATIVE CORE BIOPSY OF SOFT TISSUE TUMOURS FACILITATES THEIR SURGICAL MANAGEMENT: A 10-YEAR UPDATE

Background:  Soft tissue sarcomas (STS) are rare. More often than not, the possibility of STS is not considered preoperatively and the lesions are enucleated. Enucleation (excisional biopsy) is inappropriate for sarcomas as it compromises the planning of definitive surgery and radiotherapy. Incision...

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Bibliographic Details
Published in:ANZ journal of surgery 2008-11, Vol.78 (11), p.977-981
Main Authors: Woon, Dixon T. S., Serpell, Jonathan W.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Biopsy
Biopsy - methods
Cancer
Cancer surgery
core biopsy
Diagnosis, Differential
excisional biopsy
Follow-Up Studies
Humans
incisional biopsy
Medical diagnosis
Middle Aged
Neoplasm Staging
Preoperative Care - methods
Reproducibility of Results
Retrospective Studies
Soft Tissue Neoplasms - pathology
Soft Tissue Neoplasms - surgery
soft tissue sarcoma
Time Factors
Tumors
Young Adult
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Summary:Background:  Soft tissue sarcomas (STS) are rare. More often than not, the possibility of STS is not considered preoperatively and the lesions are enucleated. Enucleation (excisional biopsy) is inappropriate for sarcomas as it compromises the planning of definitive surgery and radiotherapy. Incisional biopsy has been regarded as the biopsy of choice by some, but it has a high rate of wound complications. The aims of the study were (i) to assess the current accuracy of core biopsy in the diagnosis of STS; (ii) to assess whether preoperative core biopsy facilitates the surgical management of soft tissue tumours; and (iii) to evaluate whether there has been an increase in the use of core biopsy before referral. Methods:  Patients with soft tissue tumours managed by a surgeon with a special interest in soft STS from 1994 to 2007 were reviewed from data collected in a database prospectively. The accuracy of core biopsy in the diagnosis of soft tissue tumours and planning of definitive surgery were assessed. Results:  Ninety‐four patients with 98 lesions were reviewed. Sixty‐eight lesions had core biopsy. The overall sensitivity of core biopsy in diagnosing soft tissue tumours was 83.6%. It has a sensitivity of 91.3% and specificity of 100% for malignant STS. For patients who had core biopsy, 95% had one‐stage surgery; those who had no core biopsy, only 45% had one‐stage surgery (P value
ISSN:1445-1433
1445-2197
DOI:10.1111/j.1445-2197.2008.04715.x