DXA-derived section modulus and bone mineral content predict long-bone torsional strength

Previous studies have used dual energy x-ray absorptiometry (DXA) scans to calculate the section modulus (Z) of adolescent and adult human femurs. The DXA-derived values of Z were assumed to be proportional to bone strength in bending and torsion. In this study we used dog (n 5), pig (n 4), and huma...

Full description

Saved in:
Bibliographic Details
Published in:Acta orthopaedica 1999, Vol.70 (1), p.71-76
Main Authors: Sarin, Vineet K, Polefka, Elizabeth G Loboa, Beaupre, Gary S, Jenny Kiratli, B, Carter, Dennis R, van der Meulen, Marjolein C H
Format: Article
Language:English
Subjects:
Absorptiometry, Photon
Adult
Animals
Biological and medical sciences
Biomechanical Phenomena
Bone Density
Cadaver
Dogs
Femur - diagnostic imaging
Femur - physiopathology
Finite Element Analysis
Humans
Investigative techniques, diagnostic techniques (general aspects)
Linear Models
Medical sciences
Osteoarticular system. Muscles
Predictive Value of Tests
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radionuclide Imaging
Reproducibility of Results
Swine
Tensile Strength
Torsion Abnormality - physiopathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Previous studies have used dual energy x-ray absorptiometry (DXA) scans to calculate the section modulus (Z) of adolescent and adult human femurs. The DXA-derived values of Z were assumed to be proportional to bone strength in bending and torsion. In this study we used dog (n 5), pig (n 4), and human (n 13) femurs covering a linear bone mineral content (BMCL) range of 0.91-6.1 g/cm. Using DXA scans, ex vivo torsional strength tests, and torsional finite element models, we assessed the validity of using the DXA-derived Z value as an indicator of strength. The correlation between BMCL and strength was r2 = 0.87 and the correlation between Z and strength was r2 = 0.86. Based on finite element results, the dog and pig section moduli were adjusted to be comparable to the human data based on cross-sectional shape and bone tissue shear strength differences. With these adjustments, the correlation between adjusted section modulus and measured strength did not improve (r2 = 0.87). These data indicate that DXA-derived section modulus can be used to predict strength over a wide range of bone sizes. However, a clear advantage of using DXA-derived section modulus rather than BMCL could not be found.
ISSN:1745-3674
0001-6470
1745-3682
DOI:10.3109/17453679909000962