Effects of Smoking Cessation on Blood Pressure and Heart Rate Variability in Habitual Smokers

We investigated the effects of 1-week of smoking cessation on ambulatory blood pressure, heart rate, and heart rate variability in 39 normotensive male habitual smokers (mean +/- SEM, 32.5 +/- 1.0 years). The ambulatory blood pressure, heart rate, and ECG R-R intervals were measured during a 24-hour...

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Bibliographic Details
Published in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 1999-01, Vol.33 (1S Suppl), p.586-590
Main Authors: Minami, Junichi, Ishimitsu, Toshihiko, Matsuoka, Hiroaki
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Blood Pressure
Blood Pressure Monitoring, Ambulatory
Electrocardiography
Heart Rate
Humans
Male
Medical sciences
Pulse
Smoking - physiopathology
Smoking Cessation
Time Factors
Tobacco, tobacco smoking
Toxicology
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Summary:We investigated the effects of 1-week of smoking cessation on ambulatory blood pressure, heart rate, and heart rate variability in 39 normotensive male habitual smokers (mean +/- SEM, 32.5 +/- 1.0 years). The ambulatory blood pressure, heart rate, and ECG R-R intervals were measured during a 24-hour period with a portable recorder (TM-2425) on the last day of 1-week smoking and nonsmoking periods. The order of the 2 periods was randomized. In the smoking period, the subjects were instructed to smoke cigarettes according to their usual smoking patterns. A power-spectral analysis of R-R intervals was performed to obtain the low-frequency (LF) and high-frequency (HF) components. The percentage of differences between adjacent normal R-R intervals >50 milliseconds (pNN50) was used as a time-domain measure of heart rate variability. The 24-hour ambulatory blood pressure was significantly lower in the nonsmoking period than in the smoking period, by 3.5 +/- 1.1 mm Hg systole [P
ISSN:0194-911X
1524-4563
DOI:10.1161/01.hyp.33.1.586