Systolic hypertension and duration of diabetes mellitus are important determinants of retinopathy and microalbuminuria in young diabetics

This cross-sectional study looked at the prevalence of microalbuminuria and retinopathy in a cohort of 926 young, Type 1 and Type 2 diabetes mellitus (DM) patients, and determined the factors which were associated with these microvascular complications. The prevalence of microalbuminuria, defined as...

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Bibliographic Details
Published in:Diabetes research and clinical practice 1999-12, Vol.46 (3), p.213-221
Main Authors: Wan Nazaimoon, W.M., Letchuman, R., Noraini, N., Ropilah, A.R., Zainal, M., Ismail, I.S., Wan Mohamad, W.B., Faridah, I., Singaraveloo, M., Sheriff, I.H., Khalid, B.A.K.
Format: Article
Language:English
Subjects:
Adult
Albuminuria - etiology
Associated diseases and complications
Biological and medical sciences
Blood pressure
Cross-Sectional Studies
Diabetes Complications
Diabetes Mellitus - urine
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - urine
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - urine
Diabetes. Impaired glucose tolerance
Diabetic Angiopathies - complications
Diabetic Retinopathy - etiology
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Humans
Hypertension - complications
Medical sciences
Microalbuminuria
Microcirculation
Middle Aged
Retinopathy
Systole
Time Factors
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Summary:This cross-sectional study looked at the prevalence of microalbuminuria and retinopathy in a cohort of 926 young, Type 1 and Type 2 diabetes mellitus (DM) patients, and determined the factors which were associated with these microvascular complications. The prevalence of microalbuminuria, defined as the albumin:creatinine ratio ≥2.5 (for males) or ≥3.5 mg/mmol (for females), was 13.4% in Type 1 DM, 69.5% in insulin-requiring Type 2 DM and 16% in Type 2 DM treated only with oral hypoglycemic agents. Compared to those with normal renal functions, these patients were older ( P≤0.01), had significantly elevated blood pressures ( P
ISSN:0168-8227
1872-8227
DOI:10.1016/S0168-8227(99)00095-9