Acitretin for lichen amyloidosus

SUMMARY We present two cases of lichen amyloidosus treated with retinoids. A 57‐year‐old Vietnamese woman has had extensive generalized recalcitrant lichen amyloidosus for 23 years. Treatment with oral etretinate (25 mg/day) for 3 years, and later oral acitretin (10 mg/day) for the past 10 years, ha...

Full description

Saved in:
Bibliographic Details
Published in:Australasian journal of dermatology 2008-05, Vol.49 (2), p.109-113
Main Authors: Choi, James YJ, Sippe, John, Lee, Stephen
Format: Article
Language:English
Subjects:
Acitretin - therapeutic use
amyloid
Amyloidosis
Amyloidosis - drug therapy
Amyloidosis - pathology
Australian Aborigine
Biological and medical sciences
Dermatology
etretinate
Female
Humans
Keratolytic Agents - therapeutic use
Lichenoid Eruptions - drug therapy
Lichenoid Eruptions - pathology
Medical sciences
Metabolic diseases
Middle Aged
Other metabolic disorders
primary cutaneous amyloid
Psoriasis. Parapsoriasis. Lichen
retinoid
Skin - pathology
Vietnamese
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:SUMMARY We present two cases of lichen amyloidosus treated with retinoids. A 57‐year‐old Vietnamese woman has had extensive generalized recalcitrant lichen amyloidosus for 23 years. Treatment with oral etretinate (25 mg/day) for 3 years, and later oral acitretin (10 mg/day) for the past 10 years, has controlled the pruritus and flattened the hyperkeratotic papules. Whenever the acitretin was ceased her symptoms flared within weeks. On each occasion reintroduction of acitretin was effective within 1–2 months. The second case is that of a 51‐year‐old Australian Aboriginal woman who had a 2‐year history of lichen amyloidosus affecting her lower legs. A 2‐month course of oral acitretin (25 mg b.d.) produced a marked improvement in both the pruritus and hyperkeratotic papules. She was then lost to follow up for 2 years, during which time her symptoms recurred.
ISSN:0004-8380
1440-0960
DOI:10.1111/j.1440-0960.2008.00434.x