Secondary extension of Hodgkin's disease to the skin with positive staining for EBV‐encoded latent membrane protein

Cutaneous involvement with Hodgkin's disease in HIV‐positive patients is infrequent. Although the large majority of these cases are pathogenetically linked to Epstein‐Barr virus, demonstration of viral oncogenes in skin involvement of Hodgkin's disease has rarely been performed. We report...

Full description

Saved in:
Bibliographic Details
Published in:International journal of dermatology 2005-12, Vol.44 (12), p.1054-1056
Main Authors: Ruiz‐Genao, D. P., Daudén‐Tello, E., G‐F‐Villalta, M. J., Fraga, J., García‐Díez, A.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
CD3 Complex - analysis
Dermatology
Epstein-Barr Virus Infections - complications
Hematologic and hematopoietic diseases
HIV Infections - complications
Hodgkin Disease - complications
Humans
Immunohistochemistry
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Leukocyte Common Antigens - analysis
Leukosialin - analysis
Lymph Nodes - chemistry
Lymph Nodes - pathology
Male
Medical sciences
Skin - chemistry
Skin - pathology
Skin Diseases - metabolism
Skin Diseases - pathology
Viral Matrix Proteins - analysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cutaneous involvement with Hodgkin's disease in HIV‐positive patients is infrequent. Although the large majority of these cases are pathogenetically linked to Epstein‐Barr virus, demonstration of viral oncogenes in skin involvement of Hodgkin's disease has rarely been performed. We report an HIV‐positive male with aggressive Hodgkin's disease and specific cutaneous involvement. The presence of Epstein‐Barr virus in cutaneous and lymph node samples could be demonstrated by a positive reaction to the Epstein‐Barr virus latent‐encoded membrane protein.
ISSN:0011-9059
1365-4632
DOI:10.1111/j.1365-4632.2005.02269.x