Infectious bovine keratoconjunctivitis antimicrobial therapy

Infectious bovine keratoconjunctivitis (IBK) is one of the most common diseases of cattle and is of major economic importance. If the primary aetiological agent, Moraxella bovis, is successfully eliminated from ocular tissues corneal ulcers heal at a constant rate. If treatment is unsuccessful ulcer...

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Bibliographic Details
Published in:Australian veterinary journal 2007, Vol.85 (1), p.65-69
Main Authors: McConnel, C.S, Shum, L, House, J.K
Format: Article
Language:English
Subjects:
Animals
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - therapeutic use
antimicrobial
antimicrobial agents
bacterial infections
Bovine
Cattle
cattle diseases
Cattle Diseases - drug therapy
disease outbreaks
Drug Administration Routes
drug delivery systems
eyes
infectious diseases
keratoconjunctivitis
Keratoconjunctivitis, Infectious - drug therapy
literature reviews
Moraxella (Moraxella) bovis - drug effects
Moraxella (Moraxella) bovis - isolation & purification
Moraxella bovis
Moraxellaceae Infections - drug therapy
Moraxellaceae Infections - veterinary
pinkeye
Treatment Outcome
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Summary:Infectious bovine keratoconjunctivitis (IBK) is one of the most common diseases of cattle and is of major economic importance. If the primary aetiological agent, Moraxella bovis, is successfully eliminated from ocular tissues corneal ulcers heal at a constant rate. If treatment is unsuccessful ulcer reoccurrence may follow initial healing. Appropriate antimicrobial selection requires knowledge of antimicrobial sensitivities and distribution in ocular tissues and tears. Drugs may be delivered to the eye in several ways: subconjunctival injection, topical application and systemic administration. While therapeutic efficacy is affected by the frequency and mode of drug delivery, variations between intensive and extensive enterprises dictate the practical method of antimicrobial delivery. Specific recommendations for antimicrobial therapies targeting Australian IBK outbreaks are dependent upon antimicrobial pharmacokinetics, drug regulations and associated costs.
ISSN:0005-0423
1751-0813
DOI:10.1111/j.1751-0813.2006.00080.x