Concurrent versus sequential methods for labor induction at term

Abstract Objective To determine the efficacy and safety of the concurrent administration of oxytocin and prostaglandin E2 (PGE2) for induction of labor at term, prompt delivery, and good maternal and neonatal outcomes. Methods In this comparative cohort study of 70 women conducted in Pakistan, 35 we...

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Bibliographic Details
Published in:International journal of gynecology and obstetrics 2007-02, Vol.96 (2), p.94-97
Main Authors: Khan, R.A, Khan, Z.E, Ashraf, O
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Cohort Studies
Delivery, Obstetric
Delivery. Postpartum. Lactation
Dinoprostone - administration & dosage
Dinoprostone - therapeutic use
Drug Therapy, Combination
Female
Gynecology. Andrology. Obstetrics
Humans
Labor
Labor, Induced - methods
Medical sciences
Obstetrics and Gynecology
Oxytocics - administration & dosage
Oxytocics - therapeutic use
Oxytocin
Oxytocin - administration & dosage
Oxytocin - therapeutic use
Pregnancy
Pregnancy Outcome
Prostaglandins
Term Birth
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Summary:Abstract Objective To determine the efficacy and safety of the concurrent administration of oxytocin and prostaglandin E2 (PGE2) for induction of labor at term, prompt delivery, and good maternal and neonatal outcomes. Methods In this comparative cohort study of 70 women conducted in Pakistan, 35 were given oxytocin and PGE2 concurrently and 35 were given the drugs sequentially for labor induction. Two-sample t tests and ×2 tests were used for the evaluation of continuous and categorical data, respectively. Results The mean induction to delivery time was shorter by 2.4 h in the concurrent treatment group ( P < 0.001), and the proportion of vaginal deliveries was higher in that group. Conclusion The concurrent method of induction of labor resulted in shorter induction to delivery time and a higher proportion of vaginal deliveries.
ISSN:0020-7292
1879-3479
DOI:10.1016/j.ijgo.2006.10.002