Metallic Striped Nanowires as Multiplexed Immunoassay Platforms for Pathogen Detection

The white stripes in the reflectance image (left; Au=0, Ag=1) correspond to Ag in Au/Ag‐striped nanowires employed in a suspended format to enable the rapid and sensitive single and multiplex immunoassays for biowarfare agent simulants. Simultaneous analysis of both the reflectance and the fluoresce...

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Bibliographic Details
Published in:Angewandte Chemie (International ed.) 2006-10, Vol.45 (41), p.6900-6904
Main Authors: Tok, Jeffrey B.-H., Chuang, Frank Y. S., Kao, Michael C., Rose, Klint A., Pannu, Satinderpall S., Sha, Michael Y., Chakarova, Gabriela, Penn, Sharron G., Dougherty, George M.
Format: Article
Language:English
Subjects:
Antibodies, Bacterial
Antibodies, Viral
Antigens, Bacterial
Antigens, Viral
biological warfare
Bioterrorism
Gold
Immunoassay - instrumentation
immunoassays
magnetic properties
nanotechnology
Nanotechnology - instrumentation
Nanotechnology - methods
Nanowires - ultrastructure
Nickel
transition metals
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Summary:The white stripes in the reflectance image (left; Au=0, Ag=1) correspond to Ag in Au/Ag‐striped nanowires employed in a suspended format to enable the rapid and sensitive single and multiplex immunoassays for biowarfare agent simulants. Simultaneous analysis of both the reflectance and the fluorescence images (right) of a mixture of nanowires enables easy identification of the antigen present.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200601104